A recessively inherited electrophoretic variant of alkaline phosphatase in chicken serum.

HE detection of bands of enzyme activity showing different rates of migration Tduring starch gel electrophoresis has been reported repeatedly in recent years. This technique has been particularly useful in genetic studies, and many cases are now known of a band or bands, termed isozymes, which are under genetic control. Such control has been demonstrated for alkaline phosphatase in bacteria ( SCHLESINGER and LEVINTHAL 1963) , Drosophila larvae (BECKMAN and JOHNSON 1964), and human serum (BOYER 1961; ARFORS, BECKMAN and LUNDIN 1963; SHREFFLER 1965). In the present study a somewhat different type of inheritance is described for alkaline phosphatase isozymes of chicken serum. Similar findings have recently been reported by LAW and MUNRO (1965).